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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRDT All Species: 8.48
Human Site: S781 Identified Species: 20.74
UniProt: Q58F21 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58F21 NP_001717.2 947 107954 S781 V M H P S G D S D T T M L E S
Chimpanzee Pan troglodytes XP_524767 1007 114679 S840 V M H P S G D S D T M M L E S
Rhesus Macaque Macaca mulatta XP_001100884 964 108890 N798 V M H P S G D N A T T M L E S
Dog Lupus familis XP_537079 945 108284 N782 V T H Q S D D N D T R V L E S
Cat Felis silvestris
Mouse Mus musculus Q91Y44 956 107296 S791 V V H T S A E S L T V L E P E
Rat Rattus norvegicus Q6MGA9 798 88032 I652 K R Q L S L D I N K L P G E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520339 426 48553 L280 L K H C N E I L K E L F S K K
Chicken Gallus gallus NP_001025845 729 80371 N583 R Q L S L D I N K L P G E K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116861 683 74548 Q537 G Q P P K P A Q Q K K G P T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13709 2038 205327 T1367 L E F S A G S T G K S G L T D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.6 84.7 81.9 N.A. 70.8 36.3 N.A. 33.4 35.3 N.A. 34.4 N.A. 23.5 N.A. N.A. N.A.
Protein Similarity: 100 93 89 87.6 N.A. 79.3 52.9 N.A. 37.9 49.4 N.A. 49 N.A. 32.3 N.A. N.A. N.A.
P-Site Identity: 100 93.3 86.6 60 N.A. 33.3 20 N.A. 6.6 0 N.A. 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 73.3 N.A. 53.3 26.6 N.A. 26.6 13.3 N.A. 6.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 10 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 20 50 0 30 0 0 0 0 0 10 % D
% Glu: 0 10 0 0 0 10 10 0 0 10 0 0 20 50 10 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 10 0 0 0 0 40 0 0 10 0 0 30 10 0 0 % G
% His: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 20 10 0 0 0 0 0 0 0 % I
% Lys: 10 10 0 0 10 0 0 0 20 30 10 0 0 20 20 % K
% Leu: 20 0 10 10 10 10 0 10 10 10 20 10 50 0 10 % L
% Met: 0 30 0 0 0 0 0 0 0 0 10 30 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 30 10 0 0 0 0 0 0 % N
% Pro: 0 0 10 40 0 10 0 0 0 0 10 10 10 10 0 % P
% Gln: 0 20 10 10 0 0 0 10 10 0 0 0 0 0 0 % Q
% Arg: 10 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % R
% Ser: 0 0 0 20 60 0 10 30 0 0 10 0 10 0 40 % S
% Thr: 0 10 0 10 0 0 0 10 0 50 20 0 0 20 0 % T
% Val: 50 10 0 0 0 0 0 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _